The causes of obstructive sleep apnea are sometimes complicated. This situation outcomes from a mix of genetic, well being, and life-style elements, lots of which haven’t been recognized. Research recommend that variations in a number of genes, every with a small impact, mix to extend the chance of growing the situation. Nevertheless, it’s unclear what contribution every of those genetic adjustments makes to illness threat. A lot of the variations have been recognized in single research, and subsequent analysis has not verified them.Genes considered related to the event of obstructive sleep apnea are concerned in lots of physique processes. These embrace communication between nerve cells, respiratory regulation, management of inflammatory responses by the immune system, improvement of tissues within the head and face (craniofacial improvement), the sleep-wake cycle, and urge for food management.Weight problems is a significant threat issue for obstructive sleep apnea as 60 to 70 p.c of people with this situation are overweight. It’s thought that extra fatty tissue within the head and neck constricts airways and stomach fats might stop the chest and lungs from totally increasing and enjoyable. Different threat elements for obstructive sleep apnea embrace alcohol use; frequent nasal congestion; and blockages of , akin to by enlarged tonsils.Obstructive sleep apnea typically happens by itself, with out indicators and signs affecting different elements of the physique. Nevertheless, it could possibly additionally happen as a part of a syndrome, akin to mucopolysaccharidosis sort I or polycystic ovary syndrome.