1.Jones, R. S., Wharton, M. J. & Buston, M. H. The place of bodily train and bronchodilator medication within the evaluation of the asthmatic youngster. Arch. Dis. Youngster. 38, 539–545 (1963).2.McNeill, R. S., Nairn, J. R., Millar, J. S. & Ingram, C. G. Train-induced bronchial asthma. Q. J. Med. 35, 55–67 (1966).three.Sly, R. M., Heimlich, E. M., Busser, R. J. & Strick, L. Train-induced bronchospasm: impact of adrenergic or cholinergic blockade. J. Allergy 40, 93–99 (1967).four.Fisher, H. Ok., Holton, P., Buxton, R. S., & Nadel, J. A. Resistance to respiration throughout exercise-induced bronchial asthma assaults. Am. Rev. Respir. Dis. 101, 885–896 (1970).5.Bierman, E. W., Kawabori, I. & Pierson, W. E. Incidence of exercise-induced bronchial asthma in youngsters. Pediatrics 56, 847–850 (1975).6.Cropp, G. J. Relative sensitivity of various pulmonary operate exams within the analysis of exercise-induced bronchial asthma. Pediatrics 56, 860–867 (1975).7.Cropp, G. J. The train bronchoprovocation take a look at: standardization of procedures and analysis of response. J. Allergy Clin. Immunol. 64, 627–633 (1979).eight.Godfrey, S., Springer, C., Bar-Yishay, E. & Avital, A. Reduce-off factors defining regular and asthmatic bronchial reactivity to train and inhalation challenges in youngsters and younger adults. Eur. Respir. J. 14, 659–668 (1999).9.Anderson, S. D. Is there a unifying speculation for exercise-induced bronchial asthma? J. Allergy Clin. Immunol. 73, 660–665 (1984).10.Carlsen, Ok. H. et al. Train-induced bronchial asthma, respiratory and allergic problems in elite athletes: epidemiology, mechanisms and prognosis: half I of the report from the Joint Process Pressure of the European Respiratory Society (ERS) and the European Academy of Allergy and Scientific Immunology (EAACI) in cooperation with GA2LEN. Allergy 63, 387–403 (2008).11.Parsons, J. P. et al. An official American Thoracic Society medical apply guideline: exercise-induced bronchoconstriction.Am. J. Respir. Crit. Care Med. 187, 1016–1027 (2013).12.Weiler, J. M. et al. Pathogenesis, prevalence, prognosis, and administration of exercise-induced bronchoconstriction: a apply parameter.Annals Allergy Bronchial asthma Immunol. 105, S1–S47 (2010).13.Weiler, J. M. et al. Bettering screening and prognosis of exercise-induced bronchoconstriction: a name to motion. J. Allergy Clin. Immunol. Pract. 2, 275–280.e277 (2014).14.Parsons, J. P. et al. Impression of exercise-related respiratory signs in adults with bronchial asthma: Train-Induced Bronchospasm Landmark Nationwide Survey.Allergy Bronchial asthma Proc. 32, 431–437 (2011).15.Parsons, J. P. et al. Prevalence of exercise-induced bronchospasm in a cohort of varsity school athletes. Med. Sci. Sports activities Exerc. 39, 1487–1492 (2007).16.Dickinson, J., McConnell, A. & Whyte, G. Prognosis of exercise-induced bronchoconstriction: eucapnic voluntary hyperpnoea challenges determine beforehand undiagnosed elite athletes with exercise-induced bronchoconstriction. Br. J. Sports activities Med. 45, 1126–1131 (2011).17.Khan, D. A. Train-induced bronchoconstriction: burden and prevalence. Allergy Bronchial asthma Proc. 33, 1–6 (2012).18.Krafczyk, M. A. & Asplund, C. A. Train-induced bronchoconstriction: prognosis and administration. Am. Fam. Doctor 84, 427–434 (2011).19.Weiler, J. M. et al. American Academy of Allergy, Bronchial asthma & Immunology Work Group report: exercise-induced bronchial asthma.J. Allergy Clin. Immunol. 119, 1349–1358 (2007).20.Caillaud, D. et al. Train-induced bronchospasm associated to completely different phenotypes of rhinitis with out bronchial asthma in major schoolchildren: the French Six Cities Examine. Clin. Exp. Allergy.: J. Br. Soc. Allergy. Clin. Immunol. 44, 858–866 (2014).21.Kuti, B. P. et al. Prevalence and components related to exercise-induced bronchospasm amongst rural college youngsters in Ilesa, Nigeria. Niger. Postgrad. Med. J. 24, 107–113 (2017).22.Ng’ang’a, L. W. et al. Prevalence of train induced bronchospasm in Kenyan college youngsters: an urban-rural comparability. Thorax 53, 919–926 (1998).23.Rundell, Ok. W. et al. Self-reported signs and exercise-induced bronchial asthma within the elite athlete. Med. Sci. Sports activities Exerc. 33, 208–213 (2001).24.Addo-Yobo, E. O. et al. Train-induced bronchospasm and atopy in Ghana: two surveys ten years aside. PLoS Med. four, e70 (2007).25.Adewumi, A. A. et al. Affiliation between exercise-induced bronchial asthma and parental socio-economic standing amongst school-aged adolescents in a semiurban neighborhood in Nigeria. J. Exerc. Rehabil. 13, 292–299 (2017).26.Anthracopoulos, M. B. et al. Bodily exercise and exercise-induced bronchoconstriction in Greek schoolchildren. Pediatr. Pulmonol. 47, 1080–1087 (2012).27.Benarab-Boucherit, Y. et al. Prevalence price of exercise-induced bronchoconstriction in Annaba (Algeria) schoolchildren.J. Bronchial asthma 48, 511–516 (2011).28.Burr, M. L., Wat, D., Evans, C., Dunstan, F. D. & Doull, I. J. Bronchial asthma prevalence in 1973, 1988 and 2003. Thorax 61, 296–299 (2006).29.Cichalewski, L. et al. Prevalence of exercise-induced cough in schoolchildren: a pilot research.Allergy Bronchial asthma Proc. 36, 65–69 (2015).30.Correia Junior, M. A. V., Costa, E. C., Sarinho, S. W., Rizzo, J. A., & Sarinho, E. S. C. Train-induced bronchospasm in a sizzling and dry area: research of asthmatic, rhinitistic and asymptomatic adolescents. Professional Rev. Respir. Med. 11, 1013–1019 (2017).31.De Baets, F. et al. Train-induced respiratory signs are poor predictors of bronchoconstriction. Pediatr. Pulmonol. 39, 301–305 (2005).32.Hong, S. J. et al. Self-reported prevalence and threat components of bronchial asthma amongst Korean adolescents: 5-year follow-up research, 1995-2000. Clin. Exp. Allergy 34, 1556–1562 (2004).33.Johansson, H. et al. Prevalence of exercise-induced bronchoconstriction and exercise-induced laryngeal obstruction in a normal adolescent inhabitants. Thorax 70, 57–63 (2015).34.Jones, A. Asymptomatic bronchial hyperreactivity and the event of bronchial asthma and different respiratory tract diseases in youngsters. Thorax 49, 757–761 (1994).35.Lin, L. L. et al. Train-induced bronchoconstriction in youngsters with bronchial asthma: an observational cohort research. J. Microbiol. Immunol. Infect. pii: S1684-118, 30196-2 (2017).36.Powell, C. V., White, R. D. & Primhak, R. A. Longitudinal research of free operating train problem: reproducibility. Arch. Dis. Youngster. 74, 108–114 (1996).37.Sudhir, P. & Prasad, C. E. Prevalence of exercise-induced bronchospasm in schoolchildren: an urban-rural comparability. J. Trop. Pediatr. 49, 104–108 (2003).38.Tripodi, S. et al. Bronchial asthma management take a look at and bronchial problem with train in pediatric bronchial asthma. Entrance. Pediatr. four, 16 (2016).39.Tsanakas, J. N., Milner, R. D., Bannister, O. M. & Boon, A. W. Free operating bronchial asthma screening take a look at. Arch. Dis. Youngster. 63, 261–265 (1988).40.Chhabra, S. Ok., Gupta, C. Ok., Chhabra, P., & Rajpal, S. Danger components for growth of bronchial bronchial asthma in youngsters in Delhi. Ann Allergy Bronchial asthma Immunol 83, 385–390 (1999).41.Jones, C. O., Qureshi, S., Rona, R. J. & Chinn, S. Train-induced bronchoconstriction by ethnicity and presence of bronchial asthma in British 9 yr olds. Thorax 51, 1134–1136 (1996).42.Rabe, Ok. F. et al. Worldwide severity and management of bronchial asthma in youngsters and adults: the worldwide bronchial asthma insights and actuality surveys. J. Allergy Clin. Immunol. 114, 40–47 (2004).43.Weiler, J. M. et al. Train-induced bronchoconstriction update-2016. J. Allergy Clin. Immunol. 138, 1292–1295.e36 (2016).44.Bonini, M. & Palange, P. Train-induced bronchoconstriction: new proof in pathogenesis, prognosis and therapy. Bronchial asthma Res. Pract. 1, 2 (2015).45.Molis, M. A. & Molis, W. E. Train-induced bronchospasm. Sports activities Well being 2, 311–317 (2010).46.Anderson, S. D., & Kippelen, P. Airway harm as a mechanism for exercise-induced bronchoconstriction in elite athletes.J. Allergy Clin. Immunol. 122, 225–235 (2008).quiz 236-227.47.Carlsen, Ok. H., Hem, E., & Stensrud, T. Bronchial asthma in adolescent athletes. Br. J. Sports activities Med. 45, 1266–1271 (2011).48.Kojima, N. et al. Train-induced bronchial asthma is related to impaired high quality of life amongst youngsters with bronchial asthma in Japan. Allergol. Int. 58, 187–192 (2009).49.Hallstrand, T. S., Curtis, J. R., Aitken, M. L. & Sullivan, S. D. High quality of life in adolescents with gentle bronchial asthma. Pediatr. Pulmonol. 36, 536–543 (2003).50.Johansson, H. et al. The connection between train induced bronchial obstruction and well being associated high quality of life in feminine and male adolescents from a normal inhabitants. BMC Pulm. Med. 16, 63 (2016).51.Value, O. J., Hull, J. H., Backer, V., Hostrup, M. & Ansley, L. The affect of exercise-induced bronchoconstriction on athletic efficiency: a scientific evaluate. Sports activities Med. 44, 1749–1761 (2014).52.GINA. World Technique for Bronchial asthma Administration and Prevention. http://ginasthma.org/2017-gina-report-global-strategy-for-asthma-management-and-prevention/ (2017).53.Beggs, S. et al. Swimming coaching for bronchial asthma in youngsters and adolescents aged 18 years and below. Cochrane Database Syst. Rev. four, CD009607 (2013).54.Mendes, F. A. et al. Results of cardio coaching on psychosocial morbidity and signs in sufferers with bronchial asthma: a randomized medical trial. Chest 138, 331–337 (2010).55.Kirkby, R. E. & Ker, J. A. Train-induced bronchial asthma in a gaggle of South African schoolchildren throughout bodily schooling lessons. South Afr. Med. J. 88, 136–138 (1998).56.Silva, L. S. P. et al. Analysis of exercise-induced bronchospasm assessed by peak move meter in overweight adolescents. Rev. Bras. Med. Esporte 17, 6 (2011).57.Smoliga, J. M., Weiss, P. & Rundell, Ok. W. Train induced bronchoconstriction in adults: proof primarily based prognosis and administration. BMJ 352, h6951 (2016).58.Yan, Ok., Salome, C. & Woolcock, A. J. Speedy methodology for measurement of bronchial responsiveness. Thorax 38, 760–765 (1983).59.Crapo, R. O. et al. Pointers for methacholine and train problem testing-1999. This official assertion of the American Thoracic Society was adopted by the ATS Board of Administrators, July 1999. Am. J. Respir. Crit. Care Med. 161, 309–329 (2000).60.Anderson, S. D., Argyros, G. J., Magnussen, H. & Holzer, Ok. Provocation by eucapnic voluntary hyperpnoea to determine train induced bronchoconstriction. Br. J. Sports activities Med. 35, 344–347 (2001).61.Caggiano, S., Cutrera, R., Di Marco, A., & Turchetta, A. Train-induced bronchospasm and allergy. Entrance. Pediatr. 5, 131 (2017).62.Brannan, J. D. et al. The protection and efficacy of inhaled dry powder mannitol as a bronchial provocation take a look at for airway hyperresponsiveness: a section three comparability research with hypertonic (four.5%) saline. Respir. Res. 6, 144 (2005).63.Anderson, S. D. et al. A brand new methodology for bronchial-provocation testing in asthmatic topics utilizing a dry powder of mannitol. Am. J. Respir. Crit. Care Med. 156, 758–765 (1997).64.Simpson, A. J., Romer, L. M. & Kippelen, P. Self-reported signs after induced and inhibited bronchoconstriction in athletes. Med. Sci. Sports activities Exerc. 47, 2005–2013 (2015).65.Teva Respiratory, L. EIB: A Landmark Survey. https://www.eiblandmarksurvey.com accessed July 2017 (2016).66.Parsons, J. P., O’Brien, J. M., Lucarelli, M. R. & Mastronarde, J. G. Variations within the analysis and administration of exercise-induced bronchospasm between household physicians and pulmonologists. J. Bronchial asthma. 43, 379–384 (2006).67.Hull, J. H., Hull, P. J., Parsons, J. P., Dickinson, J. W. & Ansley, L. Method to the prognosis and administration of suspected exercise-induced bronchoconstriction by major care physicians. BMC Pulm. Med. 9, 29 (2009).68.Fortress, W., Fuller, R., Corridor, J., & Palmer, J. Serevent nationwide surveillance research: comparability of salmeterol with salbutamol in asthmatic sufferers who require common bronchodilator therapy. BMJ 306, 1034–1037 (1993).69.Nelson, H. S., Weiss, S. T., Bleecker, E. R., Yancey, S. W. & Dorinsky, P. M. The Salmeterol Multicenter Bronchial asthma Analysis Trial: a comparability of regular pharmacotherapy for bronchial asthma or regular pharmacotherapy plus salmeterol. Chest 129, 15–26 (2006).70.Anderson, S. et al. Laboratory protocol for train bronchial asthma to judge salbutamol given by two units. Med. Sci. Sports activities Exerc. 33, 893 (2001).71.Mickleborough, T. D. L., M., R. & Turner, L. A. Comparative results of a high-intensity interval warm-up and salbutamol on the bronchoconstrictor response to train in asthmatic athletes. Int. J. Sports activities Med. 28, 456–462 (2007).72.Koh, M. S., Tee, A., LassersonT. J. & Irving, L. B. Inhaled corticosteroids in comparison with placebo for prevention of train induced bronchoconstriction. Cochrane Database Syst. Rev. three, CD002739 (2007).73.Newnham, D. M., Ingram, C. G., Earnshaw, J., Palmer, J. B. & Dhillon, D. P. Salmeterol gives extended safety in opposition to exercise-induced bronchoconstriction in a majority of topics with gentle, secure bronchial asthma. Respir. Med. 87, 439–444 (1993).74.Bonini, M. Beta-2 agonists for exercise-induced bronchoconstriction in youngsters. Paediatr. Respir. Rev. 15, 42–44 (2014).75.M. S. D. Restricted. Abstract of Product Traits. http://www.medicines.org.uk/emc/medication/17718/SPC (2015).76.Colice, G., & Calhoun, W. J. Part 2. Train-induced bronchospasm: albuterol versus montelukast: highlights of the Bronchial asthma Summit 2009: past the rules. World Allergy Organ. J. three, 23–30 (2010).77.WADA. World Anti-Doping Company. https://www.wada-ama.org/ (2018).78.IOC. Worldwide Olympic Committee Consensus Assertion on Bronchial asthma in Elite Athletes. https://stillmed.olympic.org/media/Doc%20Library/OlympicOrg/IOC/Who-We-Are/Commissions/Medical-and-Scientific-Fee/EN-IOC-Consensus-Assertion-on-Bronchial asthma-in-Elite-Athletes.pdf (2008).